World Journal of
Pharmaceutical and Life Sciences

ABSTRACT

Introduction: coronary heart disease is the leading cause of death in diabetic patients. Objective: To describe the epidemiological and diagnostic aspects of silent myocardial ischemia in diabetic patients in Conakry. Patients and methods: prospective and descriptive study lasting six (6) months (from May 1st to October 31st, 2017) in the medical and surgical emergency department of the Donka National University Hospital. The study focused on type 2 diabetic patients seen in outpatients who had an electrocardiogram. We also took into account certain risk factors such as: high blood pressure, smoking, abdominal obesity and dyslipidemia. Results: in total, 111 patients with type 2 diabetes, which we divided into two groups: patients with abnormal resting ECG (71) 64% and those with a normal resting ECG (40) 36%. The mean age of the patients was 54 ± 15 years. The electrical abnormalities were represented by: 07 epicardial lesions (9.85%); 11 cases of endocardial lesions (15.45%); 14 epicardial ischemic cases (19.72%), 12 cases of endocardial ischemia (16.96%) and 27 cases of necrosis (38.02%). The cardiovascular risk factors that were associated with the ischemic resting ECG were: hypertension (p = 0.03), abdominal obesity (p = 0.04), smoking (p = 0.02), and dyslipidemia (p = 0.01). Conclusion: this study confirms the reality of silent myocardial ischemia in Conakry with a frequency of 64% and the electrocardiogram is the first means of diagnosis.