World Journal of
Pharmaceutical and Life Sciences

PHYTOCHEMICAL SCREENING AND POTENTIAL BACTERICIDAL EFFICACY OF ANNONA SQUAMOSA LEAF EXTRACTS

S. Gowri Sankar, Dr. S. Thangapandiyan*, A. S. Alif Alisha and P. Saravana kumar

ABSTRACT

Plants have been one of the important sources of medicines since the beginning of human civilization. Extensive biological research was carried out on Annona squamosa because of the presence of valuable bioactive compounds in various parts of the plant, which are traditionally used for the treatment of many ailments. This work has been carried out to evaluate the antibacterial activity of Annona squamosa leaves. A broad range of solvents including ethanol, acetone, methanol and distilled water have been used for the extraction of bioactive compounds from plant leaves. The antibacterial activity of leaf extracts of Annona squamosa was investigated against gram positive and gram negative bacterial pathogens such as Staphylococcus aureus, Bacillus subtilis, Salmonella typhi and Escherichia coli by agar well diffusion method. From this study, it is clearly indicated that Annona squamosa leaves possess the capabilities of being a good alternative agent for bactericidal infections.

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