World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF EFFECTIVENESS OF BENEFICIAL BACTERIA IN THE TREATMENT OF MODERATE TO SEVERE CHRONIC PERIODONTITIS - A CLINICAL STUDY

Dr. Sneha S. Puri and Dr. M. L. Bhongade

ABSTRACT

Aims and Objectives: It is well known that the beneficial bacteria can suppress the emergence of pathogenic bacteria, particularly in the gastrointestinal tract. Although there is strong evidence suggesting potential effect of probiotics in the prevention of dental caries, its role in the treatment of periodontal disease is not clear. Therefore, the aim of this split mouth, controlled clinical trial was to evaluate the efficacy of beneficial bacteria (lactobacilli and bifidobacterium) as an adjunct to SRP in the treatment of moderate to severe chronic periodontitis. Material and methods: 44 sites with range of PPD 5-7mm in 10 chronic periodontitis patients (mean age of 42.7 ± 5.36 years) were treated in the present study. In each patient, 2-3 sites in one quadrant were treated by SRP+Probiotic (Test sites) while 2-3 sites in the contralateral quadrant were treated by SRP alone (Control sites). Plaque index, Papillary bleeding index (PBI), Probing pocket depth (PPD), clinical attachment level (CAL), and gingival recession were recorded at baseline and at 3 months after therapy. Results: After 3 months, patients treated with SRP+Probiotic showed a significant mean CAL gain of 2.34mm than patients treated with SRP alone 1.32mm. PPD reduction in SRP+Probiotic was significantly greater (2.77mm) compared to SRP alone (1.63mm). Conclusion: Subgingival application of probiotics adjunct to SRP showed significant improvement in all clinical parameters tested indicating beneficial effect of probiotics in periodontal therapy.

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