World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Scientific Indexing Services (SIS), Indian citation Index (ICI), Directory of Research Journals Indexing, Scintific journal impact factorScientific Journal Impact Factor (SJIF), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Cosmos Impact Factor, IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), Web of Science Group (Under Process), Research Bible, Fuchu, Tokyo. JAPAN, Scholar Article Journal Index (SAJI), Scope Database, Academia, 

Abstract

FORMULATION OF CHONDROITIN SULFATE NANOPARTICLE WITH CHITOSAN AND KAPPA CARRAGEENAN USING THE IONIC GELATION METHOD

Danni Ramdhani*, Anis Yohana Chaerunisaa and Aneu Nur Utami

ABSTRACT

Objective. Chondroitin sulfate is a widely used dietary supplement formulations, effective for the treatment of osteoarthritis. In oral preparations, chondroitin sulfate has low bioavailability. The alternative to improve bioavailability of a drug is by using nanoparticle technology. This study was aimed to formulate and characterize chondroitin sulfate nanoparticles with chitosan as polymer and kappa carrageenan as crosslinker. Methods. Nanoparticles were prepared by using ionic gelation method that was based on the electrostatic interaction between opposite charges. Results. The results showed that F1 containing 0.1% chitosan, 0.1% chondroitin sulfate, and 0.05% kappa carrageenan at volume ratio of 10: 1: 1 was the best formula with an average particle size 582.9 nm , polydispersity index value of 0.324, and zeta potential value as much as -0.47 mV.

[Full Text Article]   [Download Certificate]

WJPLS CITATION

  All Since 2019
 Citation  422  322
 h-index  9  7
 i10-index  4  2

SJIF Impact Factor 6.12  

INDEXING

Indexing

NEWS & UPDATION

    A PHP Error was encountered

    Severity: Notice

    Message: Undefined variable: news

    Filename: views/right_panel.php

    Line Number: 79

    A PHP Error was encountered

    Severity: Warning

    Message: Invalid argument supplied for foreach()

    Filename: views/right_panel.php

    Line Number: 79

BEST ARTICLE AWARDS

World Journal of Pharmaceutical and life sciences is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.

Best Article of current issue

Download Article : Click here

Downloads

  Covering Letter

  Copy Right Form

  Author Instruction

read more

Powered By WJPLS ! All Rights Reserved.

WJPLS

Follow us on: