World Journal of
Pharmaceutical and Life Sciences

ROLE OF RED CELL CALCIUM AND MAGNESIUM IN THYROID FUNCTION

Rajeswari S., Revathy K. and Swaminathan S.*

ABSTRACT

Many previous studies have established the role of metal ions like calcium (Ca) and magnesium (Mg) in controlling the thyroid hormones production as well as metabolism and hence an association may exist between thyroid hormones and the above two metals. Although many studies have been done to evaluate the role of the two principle macrometals calcium and magnesium, but all the studies were based on plasma levels of these metals which are variable. Very few studies have been done to find out the red cell content of these two metals in a variety of clinical conditions associated with altered thyroid function. The main aim of this study is an attempt to find out the association of red cell Ca and Mg to the principle thyroid hormones TSH, FT4 and FT3. Very Good correlations were observed between red cell Ca and Mg to TSH and FT4 indicating that both TSH and FT4 are indeed Ca and Mg dependent suggesting the role of both red cell Ca & Mg in regulating thyroid function. More studies are required to establish the role of red cell Ca & Mg to evaluate all types of thyroid diseases.

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