World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF ANTIBIOTICS DOXYCYCLINE: POTENTIAL TEST AND COMPARATIVE TEST OF ACTIVITY IN ANTIBIOTIC RESISTANCE CASES OF ARIS AT TASIKMALAYA CITY HEALTH CENTER, INDONESIA

Danni Ramdhani*, Sri Agung Fitri Kusuma and Resmi Mustarichie

ABSTRACT

Objective: Acute respiratory tract infection (ARIs) is a disease attacking one or more parts of the respiratory tract. The treatments of ARIs, people tend to give some antibiotics. The purpose of this study is to obtain data from the quality of antibiotics doxycyclin used viewed from the parameters of potential test and comparative test of activity against clinical isolates of patients with ARIs at Purbaratu Tasikmalaya City Health Center. This data is useful for evaluating the effectiveness of antibiotic use and determining government policy in the handling of cases of resistance. Methods: The research methods include the rejuvenation of clinical isolates, potential test, and comparative test of activity antibiotic. Results: The antibiotic potential test result is 86.8%, and the comparative test of antibiotic activity is 1: 1.03. Conclusions: The value of the antibiotic test of doxycycline has decreased based on the requirements listed on Pharmacopoeia Indonesia. Comparative tests of antibiotic activity indicate that the doxycycline samples used in community health centers have activities equivalent to antibiotic standards.

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