World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE CUCUMIS MELO VAR. FLEXUOUSAS L. (CUCURBITACEAE) FIXED OIL

Dr. Abdel Karim M.*, Inas A. and Hind A.

ABSTRACT

This study was carried out to investigate the chemical constituents of Cucumis melo var. flexuousas L seed oil and to assess its antimicrobial activity. The GC-MS analysis revealed the presence of 22 constituents dominated by: 9,12-Z,Z-octadecadienoic acid methyl ester (48.08%),9-Z-octadecenoic acid methyl ester(18.05%%), hexadecanoic acid methyl ester(15.96%), methyl stearate(11.18%). Cucumis Melo Var Flexuosus oil was assessed for antimicrobial activity against five standard human pathogens. The oil showed excellent activity against Escherichia coli at test concentration. It also showed good activity against Bacillus subtilis. However, It exhibited partial activity against Pseudomonas aeruginosa and Staphylococcus aureus.The oil also displayed weak anticandidal potency.

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