World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE ERUCA SATIVA (BRASSICACEAE) FIXED OIL

Dr. Abdel Karim M.*, Adam Y. and Khalid, M. S.

ABSTRACT

Eruca sativa seed oil was studied by GC-MS. The oil was also evaluated for antimicrobial activity. Twenty five components were detected by GC-MS analysis. Main constituents are: 13-docosenoic acid methyl ester (34.32%); (z,z)-9,12-octadecadienoic acid methyl ester(11.80%); cis-13-eicosenoic acid methyl ester(11.05%) ; 9-octadecenoic acid methyl ester (10.76%) ; hexadecanoic acid, methyl ester(6.98%) ; 9,12,15-octadecatrienoic acid methyl ester (6.41%) The antibacterial activity of the oil was evaluated via the disc diffusion bioassay against five standard pathogenic bacteria (Gram positive: Staphylococcus aureus and Bacillus subtitlis; Gram negative : Esherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans ). The oil showed excellent activity against Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli.However, it showed partial activity against Bacillus subtilis and it was inactive against the yeast Candida albicans.

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