World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

SYNTHESIS AND CHARACTERIZATION OF SOME ANTIMICROBIAL MANNICH BASES

Dr. Abdel Karim M.*, Hala I. and Tamador A.

ABSTRACT

Three Mannich bases: 2-hydroxymethyl-4-morpholinomethyl-1, 5-diphenyl-pent-1,4-dien-3-one(I); 2-acetamidomethy l-4-acetamidophenol(II) and 1-phenyl-3-(pyrrolidino-1-yl)propan-1-one(III) were synthesized via a general synthesis strategy. They were identified by spectral data (UV, IR, NMR and MS). Mannich bases I and II were evaluated for their antimicrobial potential and promising activity was observed.

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