World Journal of
Pharmaceutical and Life Sciences

PHYTOCHEMICAL SCREENING AND IN VIVO EFFECT OF HYDRO-ETHANOLIC EXTRACT OF TRILEPISIUM MADAGASCARIENSE D. C. LEEUWENBERG (MORACEAE) LEAVES ON HEMATOLOGIC PARAMETERS IN THE HEALTHY RAT

Raoul Ampa*, Cyr Jonas Morabandza, Wilfrid Arnaud Etou Ossibi, Gabriel Ahombo, Martin Diatewa, Ange Antoine Abena

ABSTRACT

Plants have an almost limitless ability to synthesize secondary metabolites that possess medicinal properties. The present work deals with the qualitative phytochemical screening and in vivo effect of hydro-ethanolic extract of the leaves of T. madagascariense, a medicinal plant widely used against anaemia. Phytochemical screening performed by coloured reactions in tubes revealed the presence of 7 chemical families; ninhydrine reagent test, revealed the presence of amino acids. Extract effect on hematologic parameters realised by blood formulates numeration after oral administration at the doses of 200, 400 and 800 mg/kg show a significant increase of hematologic parameters compare to the control: leucocytes p<0.001 and p<0.05 respectively in males and females; red globules and plates p<0.05 in males and females. These results confirm and encourage the abundant use of this species in traditional medicine against anaemia.

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