World Journal of
Pharmaceutical and Life Sciences

PATTERN OF BONY METASTASIS IN DIFFERENT TYPES OF MALIGNANCY

Dr. Arvind Kumar* and Usha Singh

ABSTRACT

Bone pain is very common in different types of malignancy and is present in one third of patients suffering from carcinoma. After liver and lung bone is the third most common site of metastatic disease. Prostate, breast, lung, kidney and thyroid cancers accounts for 80% of skeletal metastasis. The most common site of bony metastasis are spine, pelvis, ribs, skull, and proximal femur. Aim of the present study is to evaluate pattern of bony metastasis, its side, laterality in different types of carcinoma. This is a retrospective nonrandomized study of 35 patients of differents type of malignancy with bone metastasis. Age ranges from 16 years to 90 years. Majority of patients 19(54.2%) belongs to 5th and 6th decade. 11(31.4%) were male and 24 (68.5%) were female. Out of 35 patients -14(40%) were of breast cancer, 7(20%) cervical cancer patients, 4(11.4%) multiple myeloma, 4(11.4%) prostate, 4 (11.4%) head and neck cancer and 1 (2.8%) patient belongs to each group of ovary and renal cell carcinoma. Among all, spine was the most common site of metastasisi.e.in 21(60%) patients, in 18 (51.4%) patient pelvis were second common site for metastasis Third most common site was proximal end of femur. Ribs were most common site for breast cancer. Other sites were skull, sternum and scapula.

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