World Journal of
Pharmaceutical and Life Sciences

NON ADHERENCE AND ITS CONTRIBUTING FACTORS TO ANTI-TB DRUG IN CHILDREN’S AT ADAMA REFERRAL HOSPITAL, OROMIA, ETHIOPIA

Kelifa Osman Yusuf*, Muluneh Fromsa Seifu, Belayneh Kefale Gelaw, Tirumurgan Gunasekaran, Esayas Tadesse Gebremariam, Mustefa Ahmed Mohammed

ABSTRACT

Objective: The objective of this study was to assess of factors affecting adherence of pediatric TB patients to anti TB drugs in Adama referral hospital. Methodology: Retrospective cross sectional study has been conducted from March 19th to May 20th, 2014 to assess factors affecting adherence of pediatrics TB patients to anti TB drugs in Adama referral hospital. Data collection format was used to collect data from available data sources such as patients? medical cards and DOT registration book. Simple random sampling technique has been used in this research and data was presented in table and categorized and analyzed by using SPSS computer software package. Result: Among 91 patients 42(46.1%) were males and 49(53.8%) were females. And 16 (17.6%) of patients were below 5 years of age, 30(32.96%) and 45(49.5%) of patients were between age of 6-10years and between11-15 years of age, respectively. Among all pediatrics patients 59(64.83%) of them adhered to treatment program while 27(29.67%) patient defaulted (not adhered to) the treatment program. But for 5(5.5%) patients at end of program it was not known whether they defaulted or completed the treatment. At the end of treatment program 14(15.38%) of patients were cured while 6(6.6%) of the patients were not cured due to either MDRTB development or relapse, and 6(6.6%) of the patient were died. The most common factor identified to affect pediatrics adherence to anti TB medication were parents? knowledge of TB, parents relationship with provider, presence or absence of other reason like feeling better, forgetfulness and residence area. Conclusion: As this study shows 29.67% of patients did not adhere to their treatment program. Also, this study shows that adherence of pediatric patients to their medication is not only affected by patient taking medication as prescribed but also by parent knowledge of TB, parent relationship with provider, presence or absence of other reason like feeling better, forgetfulness and residence area.

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