Abstract
A COMPLETE REVIEW ON LIPOSOME IN TARGETING DRUG DELIVERY
M. Muthukumaran*, S.Nayaz, S.Navatha, P.Reddy Reshma, P.Sabeha, K. Manjula and
D.Rajeswari
ABSTRACT
Liposomes are acceptable, efficient and superior carriers and have ability to encapsulate hydrophilic and lipophilic drugs, vaccines, diagnostic agents and other bioactive agents have led to a rapid advancement in the liposomal drug delivery system. Liposomes are microparticulate lipoidal vesicles which are under extensive investigation as drug carriers for improving the delivery of therapeutic agents. This article is intended to provide an overview of liposomal drug delivery system. It has focused on the factors affecting the behavior of the liposomes in the biological environment. Structural components, Various aspects related to mechanism of liposome formation, transportations, methods of preparations characterization and stability of the liposomal drug product were also discussed in the article. Liposomes can be used as a therapeutic tool in the fields like tumor targeting, genetic transfer, immunomodulation, skin and topical therapy.
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