World Journal of
Pharmaceutical and Life Sciences

STANDARDISATION OF MURUKKAN VITAI MATHIRAI- A SIDDHA TABLET FORMULATION

Anitha John*, Gayathri Devi V, Sasikala Ethirajulu, Shyamala Rajkumar and Selvarajan S.

ABSTRACT

Herbal medicine has been commonly used over the years for treatment and prevention of diseases, health promotion and enhancement of the span and quality of life. There is lack of a systematic approach to assess their safety and effectiveness. Standardization assures the identity, purity and strength of the drug. It helps to avoid adulteration, improper substitution and there by authentication of the samples. Hence an attempt is made to establish the pharmacopoeial standards of Siddha tablet formulation Murukkan Vitai Mathirai. It is one of the most commonly used Siddha medicines for treating the ailments such as intestinal worms, abdominal bloating, distension and indigestion. In this study, the formulation was standardized by determining its organoleptic characters, powder microscopy, physico-chemical properties and HPTLC finger printing. The physico-chemical parameters such as loss on drying at 105ºC, total ash, acid insoluble ash, water & alcohol soluble extractives and pH of 10 % water extract and preliminary phytochemicals were analyzed. The microscopic standards could be used to detect the ingredients in the compound formulations and to decide the authenticity of the formulation. The physicochemical characters, HPTLC fingerprinting profile and botanical parameters together may be used for quality evaluation and standardization of Murukkan Vitai Mathirai.

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