World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ANTI-INFLAMMATORY POTENTIAL OF JUSTICIA GENANDRUSSA BURM F. AND CHARACTERIZATION OF SOME PHYTOCONSTITUENT BY GC-MS.

Narendra D.Phatangare*, Dr.K.K.Deshmukh, Dr. V.D.Murade, Dr.D. P. Hase, Dr.D.N.Raut

ABSTRACT

Justicia genandrussa Burm f. is a small tree in Acanthaceae family, traditionally used in treatment of several diseases viz., inflammation, diabetes, hypertension, wounds, pain, asthma, rheumatism etc. The present study was carried out to investigate the anti-inflammatory activity of leaves of Justicia genandrussa Burn f. The powdered leaves were successively extractedwith petroleum ether and chloroform. The result of the study showed 69.43% inhibition. Acute oral activity of crude extracts shows nil results. The GC-MS study Showed the presence of phytoconstituent like, Caryophyllene (2.13%), 5-(7a-isopropenyl-4, 5-dimethyl-octahydroinden-4-yl)-3-methyl-pent-2-enal (1.10%), 13Docosenamide, (Z) (21.86%), Squalene (1.64) etc.

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