World Journal of
Pharmaceutical and Life Sciences

THERAPEUTIC STRATEGIES FOR MANAGING BIOFILM-ASSOCIATED INFECTIONS IN LIVESTOCK: A COMPREHENSIVE REVIEW

Risav Banerjee and Trisha Bhattacharya

ABSTRACT

Biofilm-associated diseases in animals give rise to formidable challenges due to the biofilm forming bacteria shows resistance to the conventional antimicrobial therapy. These therapeutic strategies are explored in this chapter aimed at the influence of biofilm-associated pathogens in animal conditions will be lowered. Several techniques can be used for treating the biofilm-based disease in livestock, such as biofilm-penetrating antibiotics, probiotics, phage therapy, and various other methods which includes physical and mechanical intervention of ultrasound, high pressure cleaning and the ability to destroy and remove biofilms. Immunomodulation is turning up as a key, emphasizing the role of immunostimulants along with vaccines play in strengthening defence mechanism of the host against biofilm-forming pathogens. The disruptors of the biofilm, includes enzymes and specific chemicals which degrades the matrix formed by the bacterial biofilm. The integration of biosecurity measures, sanitation practices and quarantine protocols emphasize controlling the introduction and spread of biofilm-forming bacteria. The extensive research additionally emphasises the importance of routine procedures and diagnostic tools for timely diagnosis and effective implementation. highlights the relevance of multiple preventive measures in addition to therapies tailored with the distinctive features of the bacteria producing the entailed biofilm in consideration.

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