World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ACUTE MYELOBLASTIC LEUKEMIA AND COMPLEX CYTOGENETIC ABNORMALITIES IN A 16-YEAR OLD ADOLESCENT: A CASE REPORT AND LITERATURE REVIEW

Omar Moussa*, Manira Moussa, Houssein Omar, Toughza J. and Dini N.

ABSTRACT

We present the case of a 16-year-old adolescent with no significant personal or family medical history who developed acute myeloid leukemia (AML) with complex cytogenetic abnormalities. Initially, the patient was treated for prolonged fever and bilateral submandibular lymphadenopathy, with significant pancytopenia and clinical signs suggestive of a hematological disorder. The diagnosis of AML was confirmed by lymph node biopsy, bone marrow examination, and cytogenetic analysis. The patient's evolution required induction chemotherapy, followed by therapeutic intensification and the search for a bone marrow transplant donor. This case highlights the importance of cytogenetic and molecular investigations in the diagnosis and prognosis of pediatric AML.[1]

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