World Journal of
Pharmaceutical and Life Sciences

MEDIASTINAL LYMPHADENOPATHY IN SARCOIDOSIS WITH HYPERCALCEMIA: A CASE REPORT

Beevi Fathima* and Dr. Abhirama B. R.

ABSTRACT

Sarcoidosis presents as a systemic disease with persistent noncaseating granulomatous inflammation, affecting the lungs in over 90% of cases. A typical symptom of pulmonary sarcoidosis is mediastinal lymphadenopathy, which is crucial for diagnosis and monitoring. Relieving symptoms, preventing or controlling organ damage, and improving the patient's quality of life are the main goals of sarcoidosis care. This case study describes sarcoidosis with mediastinal lymphadenopathy in a 35-year-old male patient with hypercalcemia. He has been experiencing dyspnea and chest pain for the past few days. His initial laboratory testing indicated that he developed hypercalcemia and hypoparathyroidism. Prednisolone 40mg was used to treat sarcoidosis with mediastinal lymphadenopathy and hypercalcemia was treat with intravenous hydration (normal saline). After spending four days in the hospital, the patient was discharged with less calcium in the body and better symptoms. Sarcoidosis may be associated with impaired calcium metabolism. Parathyroid hormone (PTH) levels are expected to be suppressed in sarcoidosis due to increased calcium levels.

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