World Journal of
Pharmaceutical and Life Sciences

TO EVALAUTE THE EFFICACY OF LAJJALUMOOLA TAILA IN SADHYOVRANA W.S.R. TO POST-OPERATIVE FISTULOTOMY WOUNDS- A RANDOMIZED CLINICAL COMPARATIVE STUDY

Sneha K. J.* and Srinivas Masalekar

ABSTRACT

The management of Vrana (wound) is one of the primary challenges in the field of surgery. Vrana disrupts tissues (gatravichurnana) and causes discoloration (vivarnata) of the affected body part.[1] Sadhyovranas are wounds caused by trauma or external factors. Post-operative fistulotomy wound is one such wound, which is contaminated and susceptible to secondary infections and may result in delayed healing. Therefore, managing such wounds is particularly challenging. Using effective Ayurvedic formulations in such wounds is very much beneficial. In Gadanigraha, while explaining Phalashruti of „Lajjalumoola taila’, it is mentioned that this taila is effective in treating the sadhyashastraghata vrana.[2] Considering post-operative wound under sadhyovrana this study has been conducted. The results of the study are compared with effect of Jatyadi taila which also has Sadhyashastraprahara vrana as its indication and also with povidone iodine solution. Methods:45 diagnosed patients fulfilling the inclusion criteria were randomly selected and divided into three groups i.e. Group A, B and C comprising of 15 patients in each group. In Group A: lajjalumoolataila was used for dressing, in Group B: Jatyadi taila was used for dressing and in Group C: dressing was carried out with Povidone-iodine. In all groups the study was carried out for 15 days or till the complete healing of the wound whichever was earlier. Result: When the assessment criteria were statistically analysed, although all groups showed highly significant results within their own groups (p<0.0001), Lajjalumoolataila (Group A) demonstrated superior effectiveness in reducing pain, wound area and exudate, while enhancing edge contraction and promoting the formation of healthy granulation tissue. Conclusion: Lajjalumoola taila proved to be a more effective treatment for managing post-operative fistulotomy wounds compared to Jatyadi taila and Povidone iodine.

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