World Journal of
Pharmaceutical and Life Sciences

EXTRACTION AND FORMULATION OF SOME CLASSICAL HERBS FOR ENHANCING THE PLATELET COUNT

Akriti Sharma, Shivani Yadav and Mojahid Ul Islam*

ABSTRACT

Fresh Carica papaya leaves were picked daily for 7 days, Leaves were washed and the stems were removed before use. After weighing, leaves were blended without adding water or other liquids. Then the mixture was filtered to obtain a pure extract of C. papaya leaves. Finally, the volume of the extract was measured, and the extracts were stored at 4 °C until use. Papaya leaf extract could be given at any stage of the disease but for best results it should be given from the first day of fever. Classical herbs extracts could be taken as syrup; 30ml three times a day before meals for an adult and 5-10ml three times a day for a child until you have fully recovered from the illness. Decided to work on this plant to find out and compare its nutritional contents of Chlorophyll and Vitamin C in wheatgrass juice and powder with their usefulness to human being. The present works include screening of pharmacogenetics evaluation along with its preliminary phytochemical evaluation. Extraction using different organic solvents is avoided considering solubility of chlorophyll. Considering the medicinal properties of these botanical sources and selection of suitable excipients to optimize the therapeutic efficacy and mask the organoleptic properties to enhance the patient compliance. Three weeks treatment with fresh wheatgrass juice (10 ml/kg, p. o.), papaya juice (5ml/kg, p. o.) produced a significant increase in all blood cell counts. Treatment with fresh juice, methanol and acetone extracts showed significant increase in haemoglobin, RBC and WBC. The mean elevation in platelet count was observed to be 30,000/μl. The mean elevation in WBC count was observed to be 2512.5/μl. The mean increase in Platelet count is 54.45%. The mean increase in WBC count is 127.18%.

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