World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF SEEDS OF PRUNUS DULCIS

*Shalima N. K., Ayswarya K., Shitha G., Ayisha Nitha P., Aiswarya G. K., Aparna P., Dr. Biju C. R., Dr. Byju K., Dr. G. Babu and Nimmi M.

ABSTRACT

The present study was conducted to evaluate the hepatoprotective activity of ethyl acetate extract of seeds of prunus dulcis The extract at the dose of 200 mg/kg and 400 mg/kg b. wt. was tested for its hepatoprotection, by inducing hepatotoxicity with CCl4 in Wistar albino rats and using silymarin (100 mg/kg) as the reference standard. Biochemical parameters like, SGOT, SGPT, SALP and serum bilirubin were determined to assess the hepatoprotective effect. The extract has shown significant hepatoprotection in albino rats in reducing SGOT, SGPT, SALP and serum bilirubin levels.

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