Abstract
“DEVELOPMENT AND VALIDATION OF A REVERSE PHASE HPLC METHOD FOR ESTIMATION OF ARMODAFINIL IN BULK AND PHARMACEUTICAL FORMULATIONS”
Mohammed Adnan*, Sufiyan Mohd Perwaz*, Mohammed Azam Mohiuddin Adil, Syed Hafeez UR Rehman and Syed Haseeb Ul Haq*
ABSTRACT
Chromatography is a laboratory technique for the separation of a mixture. The mixture is dissolved in a fluid called the mobile phase, which carries it through a structure holding another material called the stationary phase. The various constituents of the mixture travel at different speeds, causing them to separate. The separation is based on differential partitioning between the mobile and stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation.[1]
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