World Journal of
Pharmaceutical and Life Sciences

DEVELOPMENT AND EVALUATION OF A WATER-BASED FOOT CRACK GEL USING CHIA SEED AND ALOE VERA EXTRACTS

Jilsha G.*, Lathika K., Mohammed Rinshad M. B., Sanzeera V. P., Shafana S. and Sharon Clara Thomas

ABSTRACT

This study aimed to develop and evaluate a herbal-based gel formulation for treating cracked heels, utilizing chia seed extract and aloe vera extract as key active ingredients. Chia seed extract, rich in omega-3 fatty acids, provides excellent skin hydration and antimicrobial properties, while aloe vera extract is known for its moisturizing, anti-inflammatory, and antimicrobial effects. Three formulations (F1, F2, and F3) were prepared using varying concentrations of Carbopol 934 as a gelling agent. The formulations were evaluated for organoleptic properties, homogeneity, pH, spreadability, viscosity, moisture absorption, and antimicrobial activity against Staphylococcus aureus and Escherichia coli. Results demonstrated that all formulations possessed optimal pH, homogeneity, viscosity, and spreadability, with F2 showing the most effective antimicrobial activity and overall performance. The findings suggest that the herbal-based gel formulation, particularly F2, offers a promising alternative for treating foot cracks, with further in vivo studies recommended to validate its therapeutic efficacy.

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