World Journal of
Pharmaceutical and Life Sciences

FORMULATION AND ANTIHYPERLIPIDEMIC ACTIVITY OF HIBISCUS ROSA SINENSIS

Shivani Yadav, Monika Yadav, Akriti Sharma and Mojahid ul Islam*

ABSTRACT

The present article deals with the Hibiscus rosa sinensis Linn commonly named as Gurhal (Family Malvaceae) is a popular medicinal plant found in tropical and Sub-tropical region of world. Its leaves, barks, roots and flowers have been used in the Indian traditional system as medicine to treat various diseases. Experiment was performed for antihyperlipidemic activity, the solution was left to rest for 5 min before being added with 2 mL of 7.5% w/v sodium carbonate. The resulting colour absorbance was measured at 760 nm in a UV-Vis spectrophotometer. The weighed flower samples were subjected to hot water method extraction to extract the anthocyanin. Hibiscus rosa sinensis used to treat several ailments as antioxidant anti-fertility, anti- hyperlipidaemic, anti-Inflammatory CNS depressant etc. Principal constituents reported in Hibiscus Rosa Sinensis Linn are cyanidin chloride, cyclopeptide alkaloid, ascorbic acid, riboflavin etc. Anti Hyperlipidaemic activity was evaluated in albino Wistar rats against the simvastatin used as a control. During biological evaluation, VLDL, HDL and LDL are measured. Total phenolic content and pH was measured by using digital pH meter.

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