World Journal of
Pharmaceutical and Life Sciences

IN-VITRO EVALUATION OF CELL VIABILITY STUDIES OF OROPHARYNGEAL CANCER USING SIMILAR MOLECULE – FAULDISCIPLA

Dr. Syed Ahmed Hussain*, Umaima Batool Osmani, Raheem Unnisa Shaik, Maimuna Fatima, Arshiya Tarannum, Faheem Unnisa and Nazneen

ABSTRACT

Aim: This study investigates the cytotoxic effects of Fauldiscipla, a novel platinum-based chemotherapeutic agent,
on kidney cancer cell lines. Objective: The primary objective is to evaluate the effectiveness of Fauldiscipla in
reducing cell viability and inducing cytotoxicity in comparison to Cetuximab. Research: Kidney cancer cell lines
were treated with various concentrations of Fauldiscipla. Cell viability was measured using MTT, CellTiter-Glo,
Alamar Blue, and SRB assays, while cytotoxicity was assessed using the LDH assay. Results indicated a dosedependent
decrease in cell viability and increased cytotoxicity with higher concentrations of Fauldiscipla.
Conclusion: Fauldiscipla significantly reduces cell viability in a dose-dependent manner and shows higher
cytotoxicity compared to Cetuximab. These findings suggest that Fauldiscipla could be a potent therapeutic option
for treating kidney cancer, pending further in vivo studies and clinical trials.

[Full Text Article]   [Download Certificate]