World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

IN-VIVO EVALUATION OF PREGABLIN AND 3-(AMINOMETHYL)-5-METHYLHEX-4-ENOIC ACID USING ANIMAL MODELS

Juveria*, Dr. Syed Ahmed Hussain, Atika Tahreem and Ayesha Tanveer

ABSTRACT

Antiepileptic drugs on the market now can treat 50 to 80 percent of epilepsy patients. 10-20% of patients who utilise these drugs report no improvement in seizure control. The extraction of compound chloroform has been significantly delayed. The quantity of LPO was lowered via COMPOUND. In MES-initiated shaking models, COMPOUND's antioxidant activities were demonstrated by a decrease in lipid peroxidation and a rise in glutathione levels. If the free radical rummaging movement disappears, repeat seizures may become more common. The treated bunches had different neuronal mobility than the control, meo-, and high-dose COMPOUND bunches. As compared to the control, the compound significantly boosted GABA levels, as well as DA, NA, and 5-HT.

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