Abstract
IN-VIVO EVALUATION OF PREGABLIN AND 3-(AMINOMETHYL)-5-METHYLHEX-5-ENOIC ACID USING ANIMAL MODELS
Juveria*, Dr. Syed Ahmed Hussain, Atika Tahreem and Ayesha Tanveer
ABSTRACT
Antiepileptic medications now on the market can treat 50 to 80 percent of epilepsy patients. Ten to twenty percent of patients who use these medications report no improvement in seizure control. The compound chloroform extraction has been severely delayed. The amount of LPO was reduced using COMPOUND. COMPOUND's antioxidant capabilities were demonstrated in MES-initiated shaking models by a reduction in lipid peroxidation and an increase in glutathione levels. Repeat seizures may become more prevalent if the free radical rummaging movement ceases. The neuronal mobility of the treated bunches differed from that of the control, meo-, and high-dose COMPOUND bunches. The compound dramatically increased GABA levels, as well as DA, NA, and 5-HT levels, as compared to the control.
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