World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

IN-VIVO EVALUATION OF PREGABLIN AND (S)-METHYL 3-(AMINOMETHYL)-5-METHYLHEXANOATE HYDROCHLORIDE USING ANIMAL MODELS

Dr. Syed Ahmed Hussain*, Juveria, Atika Tahreem and Ayesha Tanveer

ABSTRACT

Antiepileptic medications now on the market can treat 50 to 80 percent of epilepsy patients. 10-20% of patients who use these medications do not find any improvement in their seizure management. Extraction of compound chloroform has been severely delayed. COMPOUND reduced the amount of LPO. COMPOUND's antioxidant activities were revealed by a reduction in lipid peroxidation and an increase in glutathione levels in MES-initiated shaking models. Repeat seizures may be more frequent if the free radical rummaging movement dies. The neuronal mobility of the treated bunches differed from that of the standard, meo-, and high-dose COMPOUND bunches. As compared to the control, the compound dramatically increased the levels of GABA, as well as DA, NA, and 5-HT.

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