World Journal of
Pharmaceutical and Life Sciences

AN OVERVIEW ON RUTIN PLANT

Sadgir Sudhir Gajanan*, Madane S. G., Game G. S., Waykar V. N. and Dighe T. B.

ABSTRACT

Flavonoids are currently considered a special class of medicinal chemicals by the scientific community because of their wide range of therapeutic applications. Of them, rutin—also referred to as rutoside or vitamin P—has been studied for a variety of pharmacological effects. Rutin is an active component of numerous foods, including tea leaves, apples, and many others. These days, rutin's nutraceutical properties have been noted. The current review focusses on the most recent findings and the benefits of rutin for health. In addition, concerns related to safety pharmacology and SAR have also been addressed. Rutin's low bioavailability is a severe drawback that is mostly brought on by its low solubility in water, unstable nature, and restricted membrane permeability [table 1]. This is a significant component that prevents rutin from having any biological effects in vivo, even if it may exhibit bioactivity in several in vitro systems. Furthermore, rutin's low liposolubility makes it impractical for topical usage.

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