World Journal of
Pharmaceutical and Life Sciences

MECHANOCHEMICAL ASSISTED EXTRACTION OF BIOACTIVE COMPOUNDS

Gouri Ghatage*, Prajakta Nanavare, Prachi Khochage and Dr. Nilesh Chougule

ABSTRACT

The green method known as mechanochemical aided extraction (MCAE) provides a definite benefit in terms of extracting the required elements from natural goods in aqueous medium at room temperature and without the use of any hazardous, poisonous organic solvents. Additionally, the polysaccharides recovered using this approach have a different composition than those obtained using more traditional techniques. The following processing settings were optimized: Liquid-solid ratio of 2:1, extraction time of 48 minutes, and milling time of 30 minutes. Response surface approach design experiments were used to investigate the MCAE parameters. The experimental valueof (11.40 0.12)% matched the model's prediction under these circumstances. Common names for the evergreen Mediterranean plant Laurus nobilis L. include bay, sweet bay, bay laurel, Roman laurel, and daphne. L. nobilis leaves include lignans, proanthocyanidins, phenolic acids, and flavonoids. The successful industrial use of these important chemicals requires the development of appropriate extraction techniques that give the highest yields and extract quality. exploiting mechanochemical aid, By removing the phenolic component from L. nobilis leaf extracts, future research planning may be done more effectively, and the process of using this plant for industrial purposes can be streamlined.

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