World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

PARTHENIN: A SESQUITERPENE LACTONE FROM ANGIOSPERMIC PLANT PARTHENIUM HYSTEROPHORUS

Dr. Dhrubo Jyoti Sen*

ABSTRACT

Parthenium dermatitis is an immunologically mediated allergic contact dermatitis caused by plant extracts of Parthenium hysterophorus and related species. It is a chronic disease lasting for months to years and often lifetime with seasonal exacerbations and remissions. It is mainly caused by dried leaves and trichomes. Pollen play role, mainly in respiratory allergy. These may not pass beyond the nasal mucosa and hence more often causes allergic rhinitis rather than bronchial asthma. It is a noxious weed in America, Asia, Africa and Australia. This weed is considered to be a cause of allergic respiratory problems, contact dermatitis, mutagenicity in human and livestock. The pollen grains, airborne dried plant parts, and roots of parthenium cause various allergies like contact dermatitis, hay fever, asthma, and bronchitis in human beings. The common allergens found in this weed are parthenin, coronopilin, tetraneuris, and ambrosin.

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