World Journal of
Pharmaceutical and Life Sciences

COMPARISION OF DIFFERENCES BETWEEN CARBOPLATIN AND CISPLATIN IN TREATMENT OF SQAUMOUS CELL CARCINOMAS

Dr. Dulari Shah*

ABSTRACT

Squamous cell carcinomas (SCCs) account for a considerable fraction of cancers in different organ systems, hence effective treatment approaches are necessary to provide the best possible results for patients. Carboplatin and cisplatin are two of the chemotherapeutic drugs that have become indispensable for treating SCCs. In order to shed light on the efficaciousness, safety profiles, mechanisms of action, and therapeutic uses of carboplatin and cisplatin in the treatment of squamous cell carcinomas, this review paper compares those effects in-depth. To clarify each agent's unique properties and how they affect treatment choices, the comparison takes into account a number of factors, such as pharmacokinetics, pharmacodynamics, and toxicities. In order to identify possible predictors of treatment response and resistance, we also investigate the molecular mechanisms underlying the cytotoxic effects of carboplatin and cisplatin, investigating their interactions with DNA and cellular processes. The ultimate objective of this comparative analysis is to provide researchers and clinicians with important insights into the subtle distinctions between carboplatin and cisplatin in the management of SCCs. This is done with the aim of promoting evidence-based decision-making and enhancing patient outcomes in this difficult oncological environment.

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