World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF ANTIMICROBIAL ACTIVITY OF DIFFERENT SOLVENT EXTRACTS OF FRUITS OF MEDICINAL PLANT: ZANTHOXYULUM RHETSA ROXB DC.

Alphonso Priya*, More Jayashree and Gajbhiye P. Shrikant

ABSTRACT

Antimicrobial efficiency of various solvent extracts of the fruits (carpel and seed) of Zanthoxyulum rhetsa Roxb DC a medicinal plants of the Ruteacea family collected from the Western Ghat region were tested Escherichia coli, Salmonella typhi, Bacillus cereus, Bacillus subtilis, Methicillin-resistant Staphylococcus aureus, Staphylococcus aureus, Enterococcus faecalis, Klebsiella aerogenes, Shigella flexneri, Pseudomonas aeruginosa, Aspergillus niger Candida albicans, Aspergillus falvus and Rhizopus oryzae. Both the carpels and seeds extract Methanolic, Petroleum ether, Ethyl acetate, Chloroform, Ethanolic extracts of showed significant activity against Escherichia coli, Salmonella typhi, Salmonella aureus, Enterococcus faecalis, Klebisella aerogenes, Pseudomononas aeruginosa, Aspergillus niger, Candida albicans wheras aqueous extract showed no antimicrobial activity against all the experimental strains. The strongest antibacterial activity observed for the Methanol extracts of Seeds against S. aureus & S. typhi, Chloroform extract of seeds against S. typhi and Ethyl acetate extracts of carpels S. aureus. The strongest antifungal activity observed for the Chloroform extract of carpels against C. albicans and Petroleum extracts of seeds against A. niger. The Spectrum of activity observed in the present study may be indicative of the present study extracts of the fruits of Zanthoxyulum rhetsa Roxb DC could be a possible source to obtain new and effective herbal medicines to treat infections, hence justified the ethnic uses of Zanthoxyulum rhetsa Roxb DC against various infectious diseases.

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