World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

PHYSICO-ACOUSTIC INVESTIGATION OF BIOACTIVE SCHIFF BASE: N-((2- CHLORO-6,8-DIMETHYLQUINOLIN-3-YL)METHYLENE)-3-(5-METHYL-1HTETRAZOL- 1-YL)BENZENAMINE IN WATER-DMF AT DIFFERENT TEMPERATURES

S. A. Kamble, A. S. Kirdant*, S. G. Vedpathak and S. H. Quadri

ABSTRACT

A novel Schiff Base, N-((2-Chloro-6,8-dimethylquinolin-3-yl)methylene)-3-(5-methyl-1H-tetrazol-1-yl)benzenamine were synthesized from the condensation reaction of 3-(5-methyl-1H-tetrazol-1-yl)benzenamine and 2-chloro-6,8-dimethylquinoline-3-carbaldehyde and elemental analysis, infrared, 1H-NMR and 13C-NMR spectroscopic techniques were used to establish the formation of Schiff bases. To understand molecular interactions in solutions, physico-acoustic properties such as density, viscosity and ultrasonic velocity have been measured for the synthesized Schiff base in DMF and CHCl3 solutions of various concentrations at 300.15 ºK, 305.15 ºK, and 310.15 ºK. The experimental result data have been used to calculate various acoustic parameters, which are interpreted in terms of solute–solute and solute–solute interactions in these solvents.

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