World Journal of
Pharmaceutical and Life Sciences

NANOCRYSTAL AS DRUG DELIVERY SYSTEM

Abhishek Soni, Rajender Guleria, Ayush Thakur* and Komal Bhardwaj

ABSTRACT

A nanocrystal is a crystalline particle with at least one dimension measuring less than 1000 nanometres (nm),
where 1 nm is defined as 1 thousand-millionth of a meter (10-9 m). Nanocrystals have a wide variety of proven and
potential applications. Nanocrystals are pure drug crystals with sizes in the nanometer range stabilized or
surrounded by a thin coating of surfactant. Nanotechnology has extensive application as nanomedicine in the
medical field. Some nanoparticles have possible applications in novel diagnostic instruments, imagery and
methodologies, targeted medicinal products, pharmaceutical products, biomedical implants, and tissue engineering.
Application of nanotechnology leads to increase in bioavailability and bioactivity of phytomedicine by reducing the
size of the particles, surface modification, attaching or entrapping the phytomedicine with different polymers of
micro or nano materials. Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for
the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system
should minimize side-effects and reduce both dosage and dosage frequency.

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