World Journal of
Pharmaceutical and Life Sciences

A REVIEW ON RISK FACTORS OF LOW BONE MINERAL DENSITY IN CHRONIC KIDNEY DISEASE

Dr. Gundampati Satheesh*, Dr. S. Sumaya Parveen, Dr. Poola Thota Venkateswari, Dr. Goulla Mukunda Reddy and Dr. Seelam Sathwik

ABSTRACT

Osteoporosis, fragility fractures, and mineral bone disorder (MBD) are all linked to chronic kidney disease (CKD). Higher fracture risk, higher morbidity, and increased mortality are among the effects of CKD-MBD. Abnormalities
in calcium, phosphorus, PTH, and/or vitamin D are included in CKD-MBD, as are abnormalities in bone turnover,
mineralization, volume, linear growth, or strength; and/or calcification of arteries or other soft tissues. In order to
improve both short- and long-term results, it is imperative to comprehend the intricate pathophysiology of CKDMBD.
Treatment solutions for mineral bone disorder (MBD) associated with chronic kidney disease (CKD) should
be patient-centered. The pathogenetic or risk factors, diagnosis, and treatment of patients with CKD-MBD are the
main topics of this review. To examine the underlying pathophysiology and risk factors in greater depth as well as
to evaluate the safety and effectiveness of treatments for CKD-MBD, more research is necessary.

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