World Journal of
Pharmaceutical and Life Sciences

SOLID DISPERSIONS: AN OVERVIEW OF IMPROVING SOLUBILITY

Addanki Anusha*, Krishna Phanisri Ponnekanti, S. Rajeshwari, Madduri kavya, Vongeti Likitha, Neeraj Kulkarni and Nunavath Pavani

ABSTRACT

Solid dispersion technique is a highly efficient method for enhancing the rate at which weakly water-soluble
medicines dissolve, hence increasing their bioavailability. Water-soluble carriers are employed in the formulation
of solid dispersions to augment the pace at which poorly water-soluble drugs dissolve. The technique of dispersing
one or more active medicinal substances in a carrier at the solid state is referred to as solid dispersion. The
solubility behaviour of a medicine is a particularly difficult element to address in formulation creation, especially
when compared to traditional forms like tablets or capsules. Solid dispersion, on the other hand, offers several
advantages over these conventional dosage forms and can be created using numerous methods. This review paper
specifically examines the benefits, drawbacks, categorization, preparation methods, mechanisms, and
characterization of solid dispersions.

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