World Journal of
Pharmaceutical and Life Sciences

A CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF JATYADI GHRITA SUPPOSITORY IN THE POST OPERATIVE PAIN MANAGEMENT IN ANORECTAL DISORDERS – A CASE SERIES

Srinivasa N. V.* and Shilpa P. N.

ABSTRACT

According to international association for the study of pain, “pain is an unpleasant sensory and emotional
experience associated with acute or potential tissue damage.[1] In Ayurvedic classics vedana is considered as an
important diagnostic as well as prognostic factor. Management of any diseases is to primarily aimed at relieving
the vedana. The study was conducted on 40 randomly assigned patients at SJGAUH Hospital, Bengaluru by
dividing them into 2 groups -Group A and Group B. These groups were treated with Jatyadi ghrita rectal
suppository 1gm and Diclofenac rectal suppository 50mg respectively. Assessment of pain, burning sensation,
tenderness, and reliving sphincter spasm in Group A showed 86%, 92.5%, 75%, and 60% improvement and Group
B showed 98%, 87%, 87.5%, and 37.5% improvement respectively. Both the groups Jatyadi ghrita suppository i.e.
group A and Diclofenac suppository i.e. group B has been able to reduce Pain, burning sensation and Tenderness
with results showing statistically highly significant at p value <0.001.

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