World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

INVITRO EVALUATION OF MIDOSTAURIN AND ITS DERIVATIVE (MIDOSTAURIN HYDRATE) FOR THE TREATMENT OF ADULT ACUTE MYELOID LEUKEMIA

Farahanaaz Begum*, Dr. Syed Ahmed Hussain, Juveria Gaffar, Shaik Nazma Sultana and Sara Umm E. Hani

ABSTRACT

This research paper presents the results of an experimental study investigating the effects of Midostaurin Hydrate on various cellular assays, including MTT, Tubulogenesis, Indirect Immunofluorescence, and Western Blot Analysis. The study comprises four treatment groups: normal cells, a control cell line, a group treated with standard Midostaurin, and a group treated with Midostaurin Hydrate. The results reveal different impacts on cell viability, tubulogenesis, protein expression, and cellular morphology. These findings contribute to the understanding of Midostaurin Hydrate's potential as a therapeutic agent and its implications for future research and clinical applications.

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