World Journal of
Pharmaceutical and Life Sciences

GC-MS ANALYSIS AND APHRODISIAC ACTIVITY OF TRIAMTHEMA DECANDRA LINN.

Veeresh*, Pramod Kumar and V.Rama Mohan Gupta

ABSTRACT

Alcoholic extract of aerial parts of Trianthema decandra showed the presence of terpenoids, steroids and alkaloids. GC-MS analysis of the alcoholic extract showed presence of 20 compounds with Silane, dimethoxydimethyl, Borazine, phosphine oxide, n-Hexadecanoic acid, 9-Octadeccenoic acid are in high concentration. The extract was then tested for its Aphrodisiac activity using experimental model viz, Sexual behavior on prolonged immobilization- induced stress in rats. The acute toxicity study of alcoholic extract of Trianthema decandra was carried out for determination of LD50 up to the dose level of 2000mg/kg, extract was administered orally to rats as per the OECD guidelines no.425. The different dose were selected 1/20th, 1/10th, 1/5th of the lethal dose were taken as effective dose for the study. In prolonged immobilization-induced stress model, parameters like Mount latency, number of mounts, Thrusting were recorded simultaneously by two investigators with light provided by a 40-watt red lamp. Alcoholic extract of Trianthema decandra showed Aphrodisiac activity in a dose dependant manner. The medium and high dose treated groups have shown a significant increase in the number of mounts, thrusting and decrease in the latency. The results suggest the Aphrodisiac activity of aerial parts of Trianthema decandra and may be attributed to elevation of Testosterone, Adrenergic, Cholinergic & Dopamine levels elevation.

[Full Text Article]   [Download Certificate]