World Journal of
Pharmaceutical and Life Sciences

EFFECTIVENESS OF JUBIRKURIHLAH GEL ON WOUND HEALING IN RATS (RATTUS NORVEGICUS)

Masnun Masnun, Idayanti Idayanti, Dyah Wulan Ramadhani, Ira Oktaviani Rz and Rahimatul Uthia*

ABSTRACT

Jubirkurihlah (Ju: Jurangau, Bir: Gambir, Ku: Kunyik Bolai/Banglei, Rih: Sirih, Lah: Lada Hitam), extract is made and made into Jubirkurihlah Gel. The aim is to identify the effect of Jubirkurihlah Gel on wound healing. The research was designed quantitatively with experimental. The sample size is 100 rats (Rattus norvegicus) consisting of 25 for the Jubirkurihlah Gel intervention with a concentration of 25%, 25 using the Jubirkurihlah Gel with a concentration of 50%, and 25 using the Jubirkurihlah Gel with a concentration of 75% and 25 for the control. The experimental animals insist on two millimeters deep, and 1 centimeter long on the back. They grouped into four groups and observed until the wound healed. Data were analyzed univariately and bivariate using the ANOVA statistical test. The results of the study, Jubirkurihlah Gel is effective for Wound Healing in Rats (Rattus norvegicus), and none showed signs of inflammation in either the treatment or control. The longest healing was in the Control Group with a mean of 198 hours 64 minutes, and the lowest was the fastest using Jubirkurihlah Gel 25% (F1) with a mean of 103 hours 76 minutes. Recommendation for future research, Jubirkurihlah gel with a concentration of 25% needs to be tested on humans and needs to involve other professions, namely the Pharmacy Profession.

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