World Journal of
Pharmaceutical and Life Sciences

CONSIDERATIONS AND STRATEGIES DURING TOTAL PARENTERAL NUTRITION: STABILITY AND COMPATIBILITY IN TPN SOLUTIONS PREPARATION, COMPONENTS OF A TPN REGIMEN, RATE OF INFUSION AND RATE FLOW OF INTRAVENOUS FLUIDS, INDICATIONS, CONTRAINDICATIONS AND COMPLICATIONS

Ahmed Ahmed*, Heyam Saad Ali Noon Abubakr A. Kamil and Bushra Nasir

ABSTRACT

Total Parenteral Nutrition [TPN] has become vital in all clinical units and nearly all departments, especially the surgical unit, in hospitals and nearly in most clinical settings and home care services. It provides the major patient nutritional needs via [IV] route and proved lifesaving in clinical settings, where eternal based therapy is not possible. Despite potential advantages, it has limitations such as being expensive, Patient’s incompliance due to administration need clinical intervention and complications in prolong use especially in high concentration as in thrombosis and diabetes. Components include mainly water, electrolytes, glucose, amino acids, fats, and vitamins. Over the past decades it has been grown worldwide but unfortunately it is connected with significant mortality and morbidity. The purpose of this review is to describe considerations and strategies regarding calculation steps Of TPN Solution, components of a TPN regimen, rate of flow of intravenous fluids and rate of infusion, indications, complications, contraindications Stability and Compatibility in TPN Solutions Preparation during parenteral nutrition.

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