World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EXPLORATION OF CYTOTOXIC AND ANTIOXIDANT POTENTIAL OF PONGAMIA PINNATA (FAMILY: FABACEAE)

Amit Kumar Swain and Sunita Bhatnagar*

ABSTRACT

Leaves of Pongamia pinnata commonly known as ?karanj‘ were explored for their antioxidant and cytotoxic potential. Four extracts were prepared on polarity basis these were hexane, chloroform, acetone and methanol extracts. Phytochemical analysis of fresh leaves and extracts revealed the presence of phytoconstituents like flavonoids, tannin, sapponins and terpenoids. Methanol extract exhibited significant antioxidant potential in DPPH radical scavenging assay with 93.3% inhibition. In case of FRAP assay however, best activity was revealed by Chloroform extract. Cytotoxic potential of acetone and chloroform extract revealed more than 75% activity against brine shrimp larvae.

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