World Journal of
Pharmaceutical and Life Sciences

A CONCISE REVIEW ON CONTROLLED DRUG DELIVERY SYSTEM

Rinki Vishwakarma, Anushree Jain*, Aasma Kossar, Sapna Choubey and Rani Yadav

ABSTRACT

The drug delivery system enables the release of the active pharmaceutical ingredient to achieve a desired therapeutic response. Conventional drug delivery systems (tablets, capsules, syrups, ointments, etc.) suffer from poor bioavailability and fluctuations in plasma drug level and are unable to achieve sustained release. Without an efficient delivery mechanism, the whole therapeutic process can be rendered useless. Moreover, the drug has to be delivered at a specified controlled rate and at the target site as precisely as possible to achieve maximum efficacy and safety. Controlled drug delivery systems are developed to combat the problems associated with conventional drug delivery. Controlled drug delivery is one which delivers the drug at a predetermined rate, for locally or systemically, for a specified period of time. There has been a tremendous evolution in controlled drug delivery systems from the past two decades ranging from macro scale and nano scale to intelligent targeted delivery. Controlled release drug delivery employs drug-encapsulating devices from which therapeutic agents may be released at controlled rates for long periods of time, ranging from days to months. The review underlines the methodology of controlled drug delivery system preparation, their significance, disadvantages, detailed classification and the relevant example wherever required are demonstrated. This review will give an insight to researcher and academician a current update on the topic. In this, a different method and different processes are involved.

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