World Journal of
Pharmaceutical and Life Sciences

A COMPRESSIVE REVIEW ON FLOATING DRUG DELIVERY SYSTEM

Sayyed Khaled Hamedali*, Mayur Gokul Jayswal, Vasudev Jitendra Shama, Bagwan Wasim, Dr. Quazi Majaz and Dr. G. J. Khan

ABSTRACT

The concept behind the development of Floating Drug Delivery System in certain drawback of conventional dosages form and to overcome the certain drawback related to physicochemical properties of drug molecule (API) and related the formulation development. Controlled/Sustained release floating drug delivery system is a suitable delivery system for a drug candidate having narrow absorption window sparingly soluble and insoluble drugs, drugs those locally release in stomach by oral administration shows degradability in colon or poor colonic absorption. Floating drug delivery system is a part of Gastroretentive drug delivery system that provides continuous controlled administration of less soluble drugs at the absorption site (Targeted site). In this review information related to floating drug delivery system with their advantages, disadvantages over the conventional drug delivery system. Which are helpful in development of dosages form under the condition of pharmaceutical aspects. Various types of techniques are development on the dosages form. Review focused on formulation aspect of effervescent floating drug delivery system, floating drug delivery system its types. The purpose of the review is to compile the work going on this delivery system, floating drug delivery system. The review provides the valuable information related to pharmaceutical formulation aspect to achieve gastric retention (prolong time) and discussed the various factors affect and to overcome it.

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