World Journal of
Pharmaceutical and Life Sciences

DEMOGRAPHIC FACTORS AFFECTING HAEMODYNAMIC RESPONSE IN PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY: A PROSPECTIVE, OBSERVATIONAL STUDY

Dr. Lopamudra (Dhar) Chowdhury*, Prof. Arpita Laha, Prof. Suparna Chatterjee Dr. Soumen Das and Prof. Tamonas Chaudhuri

ABSTRACT

An observational study was undertaken to evaluate the factors affecting the haemodynamic changes during laparoscopic cholecystectomy performed under GA in 65 non-obese ASA-I & ASA- II patients of age group 18-60 years in a minimal invasive surgery O.T. at a tertiary centre, over a period of 6 months. During surgery, intra-abdominal pressure was 12mmHg and head tilt of 25 degree was maintained. Baseline parameters like age, sex, pulse, B.P., body weight, PaO2, ASA grade were recorded. Haemodynamic changes in respect to pulse, B.P., were noted intraoperatively at 10 minute intervals. The B.P. rise during operation was treated accordingly with GTN infusion. A multivariate analysis was done to elucidate any correlation between age, sex, duration of operation or ASA grade with the extent of hemodynamic change. The study revealed that there was significant rise of systolic B.P. in 78% cases, significant rise of both systolic and diastolic B.P. in 69% cases. There was no age or sex preponderance regarding significant B.P. rise. ASA grade II patients had a greater preponderance of B.P. rise and operations of duration > 60 minutes had a significant correlation with B.P. rise.

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