Abstract
CHEMISTRY AND SYNTHESIS OF CHIPPIINE-DIPPININE GROUP OF ALKALOIDS FOUND IN TABERNAEMONTANA SPECIES
*G. Pratheeksha, Dr. Pushpa Agrawal and Dr. Trilokchandran B.
ABSTRACT
The chippiine/dippinine/tronocarpine alkaloids are a group of indole alkaloids that are found in Tabernaemontana plants. They all have pentacyclic backbone structure. To date 14 alkaloids belonging to this group have been isolated. They are produced in extremely low concentrations in stem, bark and root of the plant. The chemical structure of the chippiine-dippinine alkaloids has been widely studied and various strategies for the synthesis of these alkaloids have been proposed in the past 20 years.
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