Abstract
PHARMACOVIGILANCE: AN OVERVIEW ON TRAMADOL
Pragati Singh* and Dr. Mohd Wasiullah
ABSTRACT
Pharmacovigilance, defined by the World Health Organization as ‘the science and series ofactivities relating to the detection, evaluation, understanding and avoidance of adverse effectsor any other drug-related problem’ plays an important role in ensuring that patients be givensafe drugs. India is now a preferred clinical trials port of call for drug entities to be launched.By viewing the increasing incidences, dug related mortality rate, proper identification of ADR’s, reporting, evaluation and under standing of adverse drugreaction lead stothe development of pharmacovigilance. In India, the Central Drug Standard Control Organization (CDSCO) whose headquarter is located at New Delhi regulate the PV activity. For smoothand effective working of PV a Pharmacovigilance Program of India (PvPI) was proposed andimplemented by government of India in 2010.Ithelps to detect previously unknown effectsof a drug and provides information from real-life clinical practice, throughout the life of thedrug.
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