World Journal of
Pharmaceutical and Life Sciences

A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF KOKILAKSHA PANEEYA KSHARA AND MULAKA PANEEYA KSHARA IN THE MANAGEMENT OF MUTRASHMARI WITH SPECIAL REFERENCE TO UROLITHIASIS

Dr. Anju G. Das*, Dr. Syeda Ather Fathima, Dr. Shivalingappa J. Arakeri, Dr. Geethanjali Hiremath and Dr. Mohasin Kadegaon

ABSTRACT

Acharya Sushruta is known as Father of Plastic Surgery. The branch Shalya Tantra gained more popularity during Sushruta’s period and the content of Sushruta Samhita is mainly surgery. The disease Mutrashmari is included one among Ashtamahagada by Acharya Sushruta. Acharya Sushruta described about surgery in Pravridha avastha of Mutrashmari detailly and also mentioned conservative measures before going for surgery. It is the recurrence nature of Urolithiasis which makes difficult for treatment. Paneeya kshara is a conservative therapy for the management of Mutrashmari (Urolithiasis) in Taruna avastha. A randomized clinical comparative study was conducted on 40 patients of Mutrashmari were selected from OPD and IPD of Shalya Tantra of Taranath Government Ayurvedic Medical College & Hospital, Ballari, they were divided into two equal groups. Patients of Group A were treated with trail drug i.e, Kokilaksha Paneeya Kshara and Group B were treated with standard drug i.e, Mulaka Paneeya Kshara with 20 patients in each group with Punarnavadi Kashaya as Anupana. Assessment was made on subjective parameters like Renal colic/Ureteric colic, Frequency of Micturition, Burning Micturition, Haematuria and objective parameters like Size of stone, Number of stone, Location of stone. Observations were made before and after the treatment. Assessment of Renal colic/Ureteric colic, Frequency of Micturition, Burning Micturition, Haematuria, Size of stone in Group A showed 100%, 71.4%,100%,100%, 31.15% improvement & in Group B 96.66%, 75%, 100%, 100%, 48.73% improvement respectively. The study showed that standard drug was more effective than the trial drug in the management of Mutrashmari.

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