World Journal of
Pharmaceutical and Life Sciences

IRON OXIDE NANOPARTICLES - A BOON FOR THERAPEUTIC APPLICATIONS

Rajendhran Gokul Raj, Bichandarkoil Jayaram Pratima, Ravichandiran Ragunath, Briska Jifrina Premnath, Manoj Kumar Srinivasan and Namasivayam Nalini*

ABSTRACT

Over the years, many different iron oxide nanoparticles have been evaluated for a wide range of biomedical applications. The synthesis and characterization of iron oxide nanoparticles and their therapeutic applications are summarized here. The first section of this review focuses on Iron Oxide Nanoparticles (IONPs) chemical synthesis methods such as co-precipitation, thermal decomposition, microemulsion, and sol-gel. Green IONPs are synthesized using a variety of living organisms such as bacteria, plants, fungi, yeast, virus, and algae. Most studies claim that bio-synthesized IONPs are biocompatible and do not cause cytotoxicity in healthy cells. Many different analytical techniques, such as TEM, XRD, and FTIR, are used to evaluate the physicochemical properties of iron oxide nanoparticles. Second, this review discusses the importance of iron oxide nanoparticles in biomedical science, specifically for cell labelling, tissue repair, cancer treatment, immunotherapy, and stem cell therapy. More research in biomedicine should be conducted using the aspects of IONPs.

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